For language access assistance, contact the ncats public information officer. The term syringoma is derived from the word syrinx, meaning pipe or tube. Department of pathology, faculty of medicine, dumlupinar university kutahya, turkey. Nov 14, 2016 if you have problems viewing pdf files, download the latest version of adobe reader. Syringoma is a tumor in the sweat ducts that are commonly harmless. Its rarity, potential for malignancy, and frequent misdiagnosis for other more. Rarely, a chondroid syringoma of many years duration suddenly undergoes malignant changes with widespread metastasis. First described by hirsch and helwig in 1961, chondroid syringomas css are rare, benign tumors of the skin arising from the eccrine sweat glands with tumor. This case is being reported for its rarity this is the 28 th case in literature involving ocular adnexa, its occurrence in a young patient and the need to keep this rare entity as a differential diagnosis of eyelid tumors. An 81yearold man underwent excisional biopsy of a big cylindric painless mass of the right lower eyelid, which had been present for over 23 years. Malignant chondroid syringoma is a mixed cutaneous tumor, with epithelial and mesenchymal components, which compromises principally the trunk and extremities. In the few cases studied, radiography of malignant chondroid syringoma tends to show higher signal intensity than muscle on proton sequence, and high signal enhancement with focal intermediate signal on stir short t1 inversion australas radiol 2001. Chondroid syringoma definition of chondroid syringoma by.
Collectively, dermatologic cancers are the most common form of cancer. We use cookies to offer you a better experience, personalize content, tailor advertising, provide social media features, and better understand the use of our services. An unusual localization a mebazaa 1, s trabelsi 1, m denguezli 1, b sriha 2, c belajouza 1, r nouira 1 dermatology online journal 12 1. Chondroid syringoma chondroid syringoma is a rare benign skin adnexal tumor of eccrineapocrine origin affecting commonly the head and neck region.
Ultrasonography shows well encapsulated, hyperechoic mass with radiating, hypoechoic septae. Department of radiation, oncology, gandhi medical college, bhopal, madhya pradesh, india. To the best of our knowledege, this is the second case reported in the english literature. Computed tomography demonstrated an isodense intraorbital tumor with. The chondroid syringoma is an extremely rare skin tumor most commonly found in the area of the head and neck region. These lesions present as nondescript dermal nodules which grow slowly.
Malignant chondroid syringoma agrawal 1998 the journal. Histopathologic and immunohistochemical examination showed a chondroid syringoma, an uncommon benign neoplasm of possible eccrine sweat gland origin, which occurs generally in the head and neck skin. Syringoma genetic and rare diseases information center. Aug 12, 2018 how can chondroid syringoma be prevented. Case report facial localization of malignant chondroid. Chondroid syringoma is a rare benign skin adnexal tumor, the cytological features of which have been published very rarely in the literature. Chondroid syringoma mix inflammatory infiltration scrotum. Apr, 2018 chondroid syringoma or mixed skin tumour is a rare, benign skin adnexal tumour which typically occurs in the head and neck region of middleaged patients. On histopathologic examination, the tumors were biphasic, with an epithelial component exhibiting apocrine or hair follicle differentiation and a myxoid, adipocytic, chondroid, andor fibrous stroma. Chondroid syringoma cs is a benign cutaneous adnexal tumor with epithelial and stromal components.
Chondroid syringoma or mixed skin tumour is a rare, benign skin adnexal tumour which typically occurs in the head and neck region of middleaged patients. A well circumscribed but unencapsulated, multilobulated mass centered in deep dermis or subcutaneous fat, with a prominent chondroid or myxoid stroma enveloping benign bland appearing epithelial and myoepithelial cells that form secondary structures. Chondroid syringoma is a benign growth, with little proliferative capacity. Mar 31, 2014 discussion chondroid syringoma also known as mixed tumour of the skin benign adnexal tumour with an unknownaetiopathogenesis. The name syringoma is derived from the greek word syrinx, which means pipe or tube. Chondroid syringoma cs of the orbit is an extremely rare benign. Syringoma treatment, removal, pictures, causes, surgery. This article deals with dermatologic neoplasms, also known as skin tumours. It is generally localized in the head and neck region and rarely in the extremities. Genetic and rare diseases information center gard po box 8126, gaithersburg, md 208988126 tollfree. Apr 01, 2009 benign chondroid syringoma mixed tumor discussion a chondroid syringoma is a rare mixed tumor of sweatgland origin that has both a benign and malignant form. Histopathology a cornerstone tool in diagnosis find, read.
Mixed tumors of skin are composed of both epithelial and mesenchymal components and are histologically similar to benign mixed tumors of salivary glands. Histopathologic and immunohistochemical examination showed a chondroid syringoma, an uncommon benign neoplasm of possible eccrine sweat gland. Clinicians diagnosing and treating diseases of the head and neck should be aware of these tumors. They typically comprise sweat gland elements within a prominent cartilagelike stroma.
Syringoma is a benign adnexal tumour originating from the intraepidermal portion of the eccrine duct. Mar 27, 2019 syringoma is a benign adnexal neoplasm formed by welldifferentiated ductal elements. The pathologic diagnoses were all consistent with cutaneous benign mixed tumor chondroid syringoma, pleomorphic adenoma. Chondroid syringoma cs is a rarely seen benign tumor rooted in the epithelial and mesenchymal cells of the skin. It is also called as mixed tumor of skin because of the presence of. Chondroid syringoma mixed tumor of the skin a clinicopathological study of cases. A rare case report deniztural, 1 fatihselcukbiricik, 1 feraygunver, 2 abdulkadirkar jgmaz, 1 andsuheylaserdengecti 1 division of medical oncology, department of internal medicine, cerrahpasa medical faculty, istanbul university, tr istanbul, turkey. It is usually exhibited as a slowly growing intradermal or subcutaneous nodule, typically located in the head and neck region. Currently, there are no known methods to prevent chondroid syringoma occurrence. This tumor developed slowly over 8 years causing indolor, no axil, exophtalmos of the left eye.
Chondroid syringoma is a rare benign skin adnexal tumor of eccrineapocrine origin affecting commonly the head and neck region. Because of the unremarkable clinical symptomatology of this rare tumor, the diagnosis is exclusively made retrospectively based on histological confirmation of the surgically. Giant chondroid syringoma of the lower eyelid ncbi nih. Despite its relative rarity, a benign and malignant variant have been described. Chondroid syringoma of the scrotum with mix inflammatory. Chondroid syringomas cs are rare benign mixed tumours that exhibit both epithelial and mesenchymal components, originating from the sweat glands 1. A female presented with a subcutaneous swelling on the scalp with repeated recurrence and positive regional lymph nodes. Department of pathology, hokkaido university school of medicine, kita. Rapidly growing chondroid syringoma of the external auditory canal. Hirsch and helwig named it chondroid syringoma because of the presence of sweat gland elements in a cartilaginous stroma and the histological criteria for diagnosis. Below are the links to the authors original submitted files for images.
Chondroid syringoma cs of the orbit is an extremely rare benign neoplasm. Due to their rarity, they are often clinically misdiagnosed and with the diagnosis only confirmed on histological examination. Recurrent malignant chondroid syringoma of the foot. Pdf on jan 1, 2016, kanathur shilpa and others published chondroid syringoma. Chondroid syringoma is also known as mixed tumour of the skin. The chondroid syringoma is usually a smallsized skin tumor, frequently on the head and neck. They most often arise on the skin of the head and neck. The tumour is composed of both epithelial and mesenchymal components. Jul 20, 2014 chondroid syringoma is also known as mixed tumour of the skin. It includes dermatologic cancer, which can be deadly. Dermal chondroid syringoma diagnostic histopathology. Chondroid syringoma is a cutaneous sweat gland tumor. We report a case of a 41yearold woman with orbital cs. Pilosebaceous differentiation in chondroid syringomasalama et al.
Sweat gland tumors are uncommon, and yet the chondroid syringoma mixed tumor of the skin appears most frequently on the faces of adults. Syringoma definition of syringoma by medical dictionary. Malignant chondroid syringoma mcs is a rare tumor, of the sweat gland. A mucoid aspirate, abundant chondromyxoid matrix material, and epithelial components were suggested as diagnostic criteria.
Case report facial localization of malignant chondroid syringoma. In contrast to the benign counterpart, which is common in the head and neck region, the malignant variety occurs predominantly on the trunk and extremities. A chondroid syringoma is a rare mixed tumor of sweatgland origin that has both a benign and malignant form. Article benign chondroid syringoma applied radiology. Chondroid syringoma is a benign tumor but incomplete excision can undergo malignant transformation. There is no systemic involvement and no associated conditions or disease states. Cutaneous benign mixed tumor chondroid syringoma of the ey.
Chondroid syringoma mixed tumor of the skin kunikane. For chondroid syringoma, total excision is recommended, 2. The dermatoscopy does not seem to supply any specific trait to this lesion. An 84yearold man presented with an enlarging bluish, painless subcutaneous nodule on the glabella. Pdf chondroid syringoma in a child onder sahin and. Five of the eight cases were apocrine, one of them with follicular and sebaceous differentiation. Outcomesresolutions the prognosis for chondroid syringoma is generally excellent with appropriate treatment, since it is a benign tumor. Chondroid syringoma is a cutaneous mixed tumor of salivaryglandtype usually located in the head and neck region. Chondroid syringoma, or pleomorphic adenoma of the skin, is a rare, benign skin adnexal tumor. Apocrine mixed tumour is also known as apocrine chondroid syringoma. Chondroid syringoma is a benign mixed tumor characterized by sweat gland elements in a cartilaginous stroma.
These lesions are common in patients with down syndrome. We report a case of a preauricular nodule at presentation and highlight the importance of differentiating a chondroid syringoma from a pleomorphic adenoma. Epithelial components derived from folliculosebaceousapocrine germ are evident in apocrine but not in eccrine cs. All the cases had a myxoid matrix and most also had a chondroid one. Facial localization of malignant chondroid syringoma. Pathology of chondroid syringoma mixed tumour of the skin. Clear cell syringoma are commonly associated with diabetes mellitus. They are typically found on the eyelids, but may also develop in other parts of the body with sebaceous ducts such as in the umbilicus, chest, armpits, breasts, genitals or vulva.
906 494 1006 715 290 650 488 1005 617 148 699 956 1549 235 1272 1191 370 845 1117 1315 991 802 935 1191 1574 1206 1125 1225 1019 1030 892 332 1074 355 111 970 574 545